P-TIOX Anti-Wrinkle Cream
  • P-TIOX Anti-Wrinkle Cream
  • P-TIOX Anti-Wrinkle Cream
  • P-TIOX Anti-Wrinkle Cream
  • P-TIOX Anti-Wrinkle Cream
  • P-TIOX Anti-Wrinkle Cream
  • P-TIOX Anti-Wrinkle Cream
  • P-TIOX Anti-Wrinkle Cream
  • P-TIOX Anti-Wrinkle Cream
  • P-TIOX Anti-Wrinkle Cream
  • P-TIOX Anti-Wrinkle Cream
  • P-TIOX Anti-Wrinkle Cream
  • P-TIOX Anti-Wrinkle Cream
  • P-TIOX Anti-Wrinkle Cream
  • P-TIOX Anti-Wrinkle Cream
  • P-TIOX Anti-Wrinkle Cream
P-TIOX Anti-Wrinkle Cream

 NEW BREAKTHROUGH

P-TIOX Anti-Wrinkle Cream

Peptide cream for deep-set wrinkle and pore reduction

4.8 (881)

Average rating includes incentivized reviews

RECOMMENDED FOR

  • • Dry

  • • Combination

  • • Oily

  • • Sensitive

48ml

$130.00
$150.00 $130.00 (-13%)
P-TIOX Anti-Wrinkle Cream
P-TIOX Anti-Wrinkle Cream
$130.00
$150.00 $130.00 (-13%)
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P-TIOX Cream Product Details

P-TIOX Cream is a potent wrinkle and texture-correcting moisturizer formulated to visibly smooth deep-set lines and reduce pore visibility. This anti-wrinkle cream is powered by a patent-pending formula with 10% Myrixinâ„¢, and 2% tripeptide technology that targets visible aging, pore visibility, and textural roughness. It also includes niacinamide, LHA and Tetrapeptide to enhance moisture, skin quality and radiance. Its micro-melting cream texture delivers hydration without a greasy feeling and leaves skin feeling smoother and radiant. When used with P-TIOX serum, the combination visibly enhances overall skin clarity and surface smoothness to deliver glass skin radiance in just 1 week.

Ideal for men and women seeking refined texture and clarity, P-TIOX Cream is also tested to complement neurotoxin injections.

P-TIOX Cream

SCIENCE + PROOF

Visible Results

Clinically tested to visibly correct wrinkles and pores, and improve7 skin quality parameters.

In 1 use*: Hydration is boosted by +94% in just 1 hour and provides 24-hourlong-lasting hydration. Skin barrier is strengthened by +32%.Sebum accumulation is reduced by 50% after 8 hours vs. untreated control.

In 4 weeks**: Skin is visibly smoother by +15% and brighter by +10%.

In 12 weeks***: Wrinkles are visibly reduced, 7 skin quality parametersare visibly improved including elasticity, radiance, smoothnessand tone evenness.

  • Up to -33% wrinkles
  • Up to -30% pore visibility
  • Up to +20% overall skin quality
  • Up to +30% skin smoothness​
  • Up to +30% skin tone evenness

Pair P-TIOX Cream with P-TIOX Serum for glass skin results in 1 week.

Physician-tested with neurotoxin injections:
Pair P-TIOX Cream with your in-office neurotoxin injectionsto visibly reduce wrinkles even in non-injected areas.
Tested on all skin tones and types.​

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  • 33% 

    Reduction in wrinkles

  • 30%

    Reduction in pore size

  • 20%

    Improvement in skin quality

The Science Behind P-TIOX Cream

The Biology of Aging: Wrinkles and Pore Visibility
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The Biology of Aging: Wrinkles and Pore Visibility

Wrinkle formation and pore visibility stem from interconnected changes in skin structure. UV exposure, oxidative stress, and repetitive facial movements accelerate the breakdown of collagen, elastin, and glycosaminoglycans--components that maintain skin firmness and smooth skin texture. As these decline, the skin loses its ability to bounce back, and fine lines deepen into wrinkles. At the same time, reduced elasticity, combined with sebum and dead skin cell buildup, causes pores to dilate and appear larger. These changes reflect slowed cell turnover, resulting in visible lines, uneven texture, and enlarged pores.
Patented Micro-Peptide + Myrixinâ„¢ Technology for Skin Clarity
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Patented Micro-Peptide + Myrixinâ„¢ Technology for Skin Clarity

P-TIOX Cream is formulated to help achieve visibly smooth, refined, and even-toned skin. Its patent-pending of peptide technology and Myrixinâ„¢, a proprietary flavonoid-rich complex inspired by neurotoxin-like effects, targets deep-set wrinkles, and pore dilation with precision. When paired with P-TIOX serum, the two-step routine addresses both superficial and structural aging markers, delivering comprehensive improvements in tone, texture, and radiance for a visibly healthier complexion.
A Targeted Partner for Neurotoxin Procedures
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A Targeted Partner for Neurotoxin Procedures

Whether used alongside deep wrinkle injections or neurotoxin injections, P-TIOX Cream is formulated to complement the visible effects of aesthetic procedures. The cream’s active technologies help optimize skin responsiveness to these treatments by improving texture, reducing pore visibility, and enhancing wrinkle correction and radiance in non-injected areas. As part of an integrated skincare approach, P-TIOX Cream supports a more comprehensive correction by addressing surface concerns, treatment gaps, and even deep wrinkles that in-office neurotoxins alone may not fully target.

How to Use P-TIOX Cream

1

Prep + Dispense

Twice daily, after applying a corrective serum, dispense a small amount into clean hands.

2

Apply + Complete

Gently press cream evenly into skin on face, neck and around the eyes. Follow with a SkinCeuticals sunscreen.

FAQ

Answers to your frequently asked
P-TIOX Cream questions.
How does P-TIOX Cream work?

P-TIOX Cream uses a patented combination of proprietary Myrixinâ„¢ and tripeptide technologies to visibly reduce deep-set wrinkles, refine texture, and help minimize the appearance of enlarged pores. Myrixinâ„¢ helps modulate oil activity, while the tripeptide supports structural firmness and surface smoothness.

This protective gel cream contains water-bursting micro-droplets that melt into the skin for rapid absorption, delivering instant smoothing and visible texture correction.
How long does it take for P-TIOX Cream to work?

Visible improvements, such as reduced pore visibility, can be seen in as little as one month. Continued daily use helps improve the appearance of deep-set wrinkles and refine overall texture. For optimal results, P-TIOX Cream should be used consistently and paired with P-TIOX serum to support the full glass skin routine.
Can you use P-TIOX Cream with retinol?

Yes, P-TIOX Cream can be used in a routine that includes retinol. During your nighttime routine, apply P-TIOX cream after the retinol. As with any skincare combination, monitor skin tolerance and consult your skincare professional if needed.
Can you use P-TIOX Cream under the eyes?

Yes, you can apply P-TIOX Cream around the eyes. Follow the instructions to apply the cream twice daily to face, neck, and around the eyes. Clinical testing for P-TIOX Cream showed -28% under eye line correction.
Is P-TIOX Cream suitable for men’s skin?

Yes. P-TIOX Cream is well-suited for men’s skin, which often exhibits higher oil production, and more visible pores. This anti-wrinkle cream’s patented Myrixin™ and tripeptide technologies help refine texture, reduce pore appearance, and oil production, all common concerns in men’s skincare.

The lightweight, non-greasy formula melts into the skin, absorbing quickly and supporting smoother, clearer skin without heaviness. This makes it an effective daily moisturizer for men seeking visible improvement in skin clarity and surface refinement.
What are the key differences between P-TIOX Serum and P-TIOX Cream?

P-TIOX Serum is a concentrated treatment that targets visible expression lines and supports skin smoothness resulting in glass skin radiance with a fluid, transparent formula. P-TIOX Cream complements the serum by addressing pores, deep-set wrinkles, and surface texture while delivering hydration in a fresh cream texture that leaves a non-greasy finish. Used together, they create a complete routine for achieving a glass skin effect.
What is glass skin and how can I achieve it?

Glass skin refers to a complexion that appears visibly smooth, luminous, and poreless. Achieving this look involves skincare that targets texture, clarity, and hydration. P-TIOX Cream helps refine texture and reduce shine, and when paired with P-TIOX Serum, contributes to achieving a visibly radiant, even-toned complexion.
Is P-TIOX Cream safe to use after neurotoxin injections?

Yes. P-TIOX Cream is designed to complement neurotoxin injections by helping prolong visible results and supporting smoother skin texture. It is suitable for post-procedure use, though you should always consult your provider for personalized post-treatment care.

Reviews

KaitlynF
Verified Buyer
I recommend this product
4 days ago
Confidence Booster!
I used this product for 30 days straight. This has been a game changer in my opinion. I’m 25 and unfortunately have forehead wrinkles from facial expressions and dehydration but SkinCeuticals has made me so much more confident. I wish I could have started using this product at 20 instead of 25 because it’s just that good. I have very sensitive skin and this doesn’t burn me at all. It’s smooth and cold when you apply it. There isn’t a smell. It feels so nice and refreshing when I apply it to my face. This will 100% be a staple in my skincare routine moving forward.
KaitlynF
KaitlynF
KaitlynF
KaraL
Verified Buyer
I recommend this product
13 days ago
I feel like it helps
I’ve been using this for over a month. This does a great job at keeping my oily skin moisturized without overly greasy. I waited too long to get my Botox last time, so this has been helping me get rid of fine lines. I also love that it’s not sticky and does not make my blackheads worse, which is my biggest pain point with my skin.
KaraL
KaraL
KaraL
JacquelineS
Verified Buyer
I recommend this product
15 days ago
Great ingredients great results
Great ingredients for the skin. Makes skin feel so smooth and hydrated. I feel my pores are less noticeable. I apply it to my face and neck. I have really dry skin and this does the job for me. Recommend!
JacquelineS
DeniseT
Verified Buyer
I recommend this product
21 days ago
Luxurious
I love the sleek design of the jar. It goes onto the skin like silk. I could tell a difference in my skin in no time. It out performed any of my other products.
DeniseT
DeniseT
DeniseT
AlejandraR
Verified Buyer
I recommend this product
23 days ago
Perfect to correct new wrinkles
I have been trying this Anti-wrinkle cream for over a month and I have definitely seen that my wrinkles are less pronounced since I started using this cream, I really like the lightweight formula, the texture is also really good and easy to apply to my face, my face is sometimes sensitive to creams but I didn’t have any reaction to this cream so I am also very thankful for that. I absolutely loved it and will definitely buy this again.
AlejandraR